Detalhe da pesquisa
1.
PD-L1 engagement on T cells promotes self-tolerance and suppression of neighboring macrophages and effector T cells in cancer.
Nat Immunol
; 21(4): 442-454, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152508
2.
The αvß6 integrin is transferred intercellularly via exosomes.
J Biol Chem
; 290(8): 4545-4551, 2015 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25568317
3.
αvß6 integrin is required for TGFß1-mediated matrix metalloproteinase2 expression.
Biochem J
; 466(3): 525-36, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25558779
4.
Effects of a human compact anti-ErbB2 antibody on gastric cancer.
Gastric Cancer
; 17(1): 107-15, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23460348
5.
CRISPR Screening Identifies Mechanisms of Resistance to KRASG12C and SHP2 Inhibitor Combinations in Non-Small Cell Lung Cancer.
Cancer Res
; 83(24): 4130-4141, 2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37934115
6.
Mechanisms of cardiotoxicity associated with ErbB2 inhibitors.
Breast Cancer Res Treat
; 134(2): 595-602, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22674190
7.
Comparison of preclinical cardiotoxic effects of different ErbB2 inhibitors.
Breast Cancer Res Treat
; 133(2): 511-21, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21947749
8.
Combined Inhibition of SHP2 and CXCR1/2 Promotes Antitumor T-cell Response in NSCLC.
Cancer Discov
; 12(1): 47-61, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34353854
9.
Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C.
Cancer Discov
; 12(6): 1500-1517, 2022 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35404998
10.
Selective and noncovalent targeting of RAS mutants for inhibition and degradation.
Nat Commun
; 12(1): 2656, 2021 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33976200
11.
SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling.
J Exp Med
; 218(1)2021 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33045063
12.
Prostate cancer sheds the αvß3 integrin in vivo through exosomes.
Matrix Biol
; 77: 41-57, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30098419
13.
SHP2 Inhibition Prevents Adaptive Resistance to MEK Inhibitors in Multiple Cancer Models.
Cancer Discov
; 8(10): 1237-1249, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30045908
14.
Exosomal αvß6 integrin is required for monocyte M2 polarization in prostate cancer.
Matrix Biol
; 70: 20-35, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29530483
15.
Exosome-mediated Transfer of αvß3 Integrin from Tumorigenic to Nontumorigenic Cells Promotes a Migratory Phenotype.
Mol Cancer Res
; 14(11): 1136-1146, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27439335
16.
αvß6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor.
Cancer Res
; 76(17): 5163-74, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27450452
17.
Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts.
Oncotarget
; 6(16): 14318-28, 2015 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26015409
18.
IGF-IR promotes prostate cancer growth by stabilizing α5ß1 integrin protein levels.
PLoS One
; 8(10): e76513, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24130778
19.
Effects of a human compact anti-ErbB2 antibody on prostate cancer.
Oncol Rep
; 28(1): 297-302, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22505344
20.
A novel ErbB2 epitope targeted by human antitumor immunoagents.
FEBS J
; 278(7): 1156-66, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21288302